Polio, a crippling and potentially deadly infectious disease, has been a persistent scourge in Pakistan for decades. Despite ongoing efforts to eradicate the virus, the third case of the ongoing year was reported in Balochistan. The previous two cases were also identified in other districts of the southwestern province. There’s ample evidence to suggest that an end to the long-drawn-out fight is nowhere in sight as the country continues to face significant challenges in combating the spread of polio. Pakistan is grappling with a resurgence of polio cases. To deny this would be a gross miscalculation as it, along with Afghanistan remains the last frontier in the global fight to end the endemic disease. This alarming trend, where the virus seems to have found refuge in Karachi, Quetta, Khyber Pakhtunkhwa, and the tribal belt underscores the urgent need for immediate action to address the root causes of the polio crisis in Pakistan. Just last year, six polio cases were reported across the length and breadth of the country to serve as a wake-up call for the authorities Misinformation and rumours surrounding the polio vaccine have led to vaccine hesitancy among communities in Pakistan. Some believe that the vaccine is unsafe or ineffective, leading to a decline in vaccination rates and leaving children vulnerable to the virus. Efforts to combat polio misinformation in Pakistan are crucial in addressing the root causes of the polio crisis. Although health authorities, civil society organizations, and community leaders are already trying their utmost best to educate the public about the importance of vaccinations, more still needs to be done to help build trust and confidence. Vaccine literacy campaigns should be increasingly tailored to address specific concerns and misconceptions within different communities. Perhaps, building trust and rapport with local communities might be the solution the state has been looking for after all. Engaging with community leaders, religious authorities, and influencers can help dispel misinformation. It is only through collaborative efforts that we stand a chance at defeating poliovirus that wishes to obstruct the future of millions of our children. *