Regional and political rifts are emerging in many countries over how fast to lift the lid on the coronavirus lockdowns, as worries about economic devastation collide with fears of a second wave of deaths. French mayors are resisting the government´s call to reopen schools, while Italian governors want Rome to ease lockdown measures faster. As the British government looks to reopen the economy, Scottish leader Nicola Sturgeon has warned that acting too fast could let the virus wreak havoc again. “Any significant easing up of restrictions at this stage would be very, very risky indeed,” Sturgeon said Thursday. The economic damage around the globe mounted. In the US, nearly 3.2 million laid-off workers applied for unemployment benefits last week, the government announced, bringing the running total over the past seven weeks to 33.5 million. When the nation’s April unemployment rate comes out on Friday, it is expected to be as high as 16%, a level not seen since the Depression. Neiman Marcus, the 112-year-old luxury retailer, filed for Chapter 11 bankruptcy, the first US department store chain to be toppled by the outreak. And the Bank of England projected that Britain´s economy will shrink by 14 percent this year, its biggest decline since 1706, when Europe was locked in the War of the Spanish Succession. In Britain, where the official death toll stands at more than 30,000, second only to the United States, Prime Minister Boris Johnson was expected to extend a more than six-week lockdown on Thursday but hopes to ease some restrictions on economic and social activity starting next week. Johnson said the government will act with “maximum caution” to prevent a second wave of infections. As governments grapple with when to restart their economies, the Trump administration has shelved a Centers for Disease Control and Prevention document with step-by-step advice to local authorities on how and when to reopen restaurants and other public places. The 17-page report with detailed instructions on what precautions to take was supposed to be published last Friday, but agency scientists were told it “would never see the light of day,” according to a CDC official who was not authorized to discuss the matter and spoke to The Associated Press on condition of anonymity. In France, more than 300 mayors in the Paris region have urged President Emmanuel Macron to delay the reopening of schools, set for Monday. Many mayors around the country have already refused to reopen schools, and many parents will keep their children home even where they are functioning again. The mayors called the timing “untenable and unrealistic,” saying they were put on a “forced march” to get schools ready without enough staff or equipment. They complained that the government guidelines were too vague and slow in coming. But governments are also under pressure to reopen faster and kick-start economies that have been plunged into hibernation. Italian regional governors are pressing to open shops and restaurants, just days after the country began easing its two-month lockdown by allowing 4.5 million people to return to work in offices and factories. Governors want to be allowed to present their own plans for reopening, tailored to the rate of infection and economic needs of their regions. After an outcry from the nation´s Roman Catholic bishops, Italian Premier Giuseppe Conte announced that public Masses will be allowed to resume on May 18. In Spain, support for the government is crumbling after seven weeks of a strict lockdown, with some regions and opposition parties demanding an end to the state of emergency declared on March 14. The government argues that it is far too soon. Some of Germany´s 16 powerful state governments are more impatient than others to open up businesses such as restaurants and hotels. At a meeting Wednesday with Chancellor Angela Merkel, it was agreed that state leaders would have wide leeway to decide when to open more sectors of the economy. They also will have to reimpose restrictions locally if infections rebound. In Russia, where the number of new infections is growing fast, President Vladimir Putin delegated the enforcement of lockdowns and other restrictions to regional governments, leading to wide variations across the country. Mikhail Vinogradov, head of the St. Petersburg Politics think tank, told the Vedomosti newspaper that the Moscow government is sending mixed messages that governors find hard to decipher – wanting a victory over the virus, while also encouraging easing of the lockdown.