In Pakistan, around 14 percent of the children die of pneumonia, a condition which has remained unchanged for the past two decades. This was stated during a seminar in Islamabad on Friday. Pneumonia continues to be one of the leading killers of children under five globally, with one child dying of the disease every 30 seconds. Although it is a long-standing issue, pneumonia remains neglected at policy level across the country. It is imperative that a high-quality evidence base, providing sustainable, scalable solutions, is generated in order to attract policy-level attention and in turn decrease the burden of disease.With over a decade of experience conducting high quality research in childhood pneumonia, Maternal, Neonatal and Child Health Research Foundation (MNCHRN) are helping to address these issues as part of the NIHR Global Health Research Unit on Respiratory Health (RESPIRE). Funded by the UK’s National Institute for Health Research (NIHR) and coordinated by the University of Edinburgh, RESPIRE is a global partnership which aims to reduce the impact and number of deaths caused by respiratory diseases in Asia.MNCHRN are implementing projects in Pakistan to generate evidence at three levels of the healthcare system. The research, funded by RESPIRE, will identify and target gaps to manage the burden of pneumonia At the community level, researchers are exploring the perceptions of caregivers on pneumonia and the related requirement for care-seeking. This will be followed by an investigation on the use of mobile health technology to aid the community in prevention of pneumonia through Lady Health Workers (LHW).Another project is identifying the current pneumonia management practices being followed by healthcare professionals at LHW, Basic Health Unit (BHU), Rural Health Centre (RHC) and practitioner level (both public and private). A third project is aimed at policy level, evaluating the pneumonia related policy environment. Data will be presented to the relevant government departments to re-visit the process of policy making regarding pneumonia control strategies in Pakistan Another major aspect of RESPIRE Pakistan is stakeholder engagement, both at community and policy level, where MCNHRN have established engagements through LHWs, Health Ministry Officials and development partners.Results of the already accomplished phases of the projects show an alarming situation where, despite extensive training of healthcare professionals, pneumonia management practices are far from the standard World Health Organisation (WHO) management guidelines.Similarly, the perceptions of caregivers regarding pneumonia in children under five years old and related care seeking is also poor, showing the need for awareness generation. Finally, despite the development of multiple policies, the focus on under-five pneumonia is very limited and the content focuses more on burden and treatment rather than prevention.