To explore the antimicrobial potential of Eucalyptus and its use as an alternative growth promoter to antibiotics, Dr. Assad Ullah, a PhD scholar in the Institute of Microbiology, UVAS, Lahore conducted research on “Evaluation of antimicrobial, immune modulatory and growth enhancing effect of ethanolic extract of Eucalyptus globulus leaves in broiler chicks” under the supervision of Prof. Dr. Aftab Ahmad Anjum. This study was part of HEC funded research project entitled “Replacement of low-level antibiotic feeding with extracts of medicinal plants in poultry”. The experiment was devised to characterize the ethanolic extract of E. globulus as a replacement of low levels of antibiotic in poultry feed.
The research was mainly based on the replacement of the use of low level of antibiotics in poultry feed. Fresh leaves of Eucalyptus were collected, dried and grinded into powder for extraction of ethanolic extract. The cellular and embryo toxicity of the plant extract was determined through MTT assay and in-ovo inoculation. The safe dose of the plant extract based on MTT assay was added in poultry feed. The birds were vaccinated and weight gain and feed conversion ratio of birds were calculated. The birds were also challenged with the common poultry pathogens to check the in-vivo antibacterial activity of the plant extract. The gut absorption was significantly improved in birds which received the ethanolic extract of the Eucalyptus, showed better immune response to vaccines and increased feed conversion ratio as compared to birds given low levels of antibiotics.
It is estimated that use of Eucalyptus extract costs about four times lesser per bag in comparison to antibiotic cost. In this way, its use can heavily reduce antibiotic import bill of the country used in feed mills.
In conclusion, birds fed with Eucalyptus extract showed better growth and high immune response as compared to antibiotic fed birds. It was suggested that Eucalyptus can be used as an alternative to antibiotics to reduce the burden of antibiotic resistance in human pathogens.
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