The research is about finding the effectiveness of hydroxychloroquine alone and adjuvant with azithromycin in mild to severe Covide-19 pneumonia patients admitted to Coronavirus block of Ayub Teaching hospital, Abbottabad Pakistan.
Coronavirus pandemic put a lot of lives at stake. By 9 April 2020, a total of 1,532,424 confirmed cases with 89,716 being dead and 337,468 recovered cases have been reported. The pre-pathogenic course of novel COVID-19 is yet to be determined, so the risk factors, clinical picture and medical intervention too. Only supportive therapy is being practiced, yet many trials of antimalarial drug, chloroquine, and quinolone is currently taking place worldwide. According to Cortegiani A, 23 ongoing trials from China have been registered. Clinical experience from the recent Wuhan epidemic came up with promising results of chloroquine and hydroxychloroquine in COVID-19 positive patients.
The website https://clinicaltrials.gov/ct2/show/NCT04328272 is maintained by the National Library of Medicine (NLM) at the National Institutes of Health (NIH). The National Institutes of Health (NIH) is an important US health agency. It is devoted to medical research. Administratively under the Department of Health and Human Services (HHS), the NIH consists of 20-some separate institutes and centres.
Inclusion Criteria of the patients would be the Confirmed cases of COVID-19 (all by RT-PCR from the same laboratory), Mild to severe clinical presentation (identified at the time of admission to ward by National Early Warning Score NEWS-2; mild 0-4; severe 5-6).
It is indeed a proud moment for Pakistan that Doctors are not only managing this Coronavirus pandemic but also focusing on the research to find the solution to treat these diseases. Ayub Medical Teaching Hospital is a 1400 bedded, tertiary healthcare facility in north Pakistan, providing health facilities to millions of Patients while Ayub Medical College has produced more than 8000 renowned doctors and surgeons, who are serving globally.
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